Morphoneuroimmunoendocrine relationships in local (tissue) homeostasis of the skin epidermis and its barrier-protective functions. Part 2

Morphoneuroimmunoendocrine relationships in local (tissue) homeostasis of the skin epidermis and its barrier-protective functions. Part 2

Blog Article

The review continues click here the series of planned articles on the morphoneuroimmunoendocrine system of the skin (MNIESS).In this review the origin, structure and functions of epidermal cells: keratinocytes, dendritic Langerhans cells, dendritic gamma/delta T-lymphocytes, Merkel cells are given further consideration to.The mechanisms of keratinization and formation of keratinosomes, formation of the epidermal lipid barrier are described in detail.

The role of ceramides, fatty acids and cholesterol in the creation process of the epidermal lipid barrier, the horny envelope and proteins involved in its formation is also considered.The causes, mechanisms of exfoliation and its significance in the barrier-protective function of the skin are discussed.The innervation of the skin (nervous component of MNIESS) is described in detail.

The ways of penetration of the liquid into the epidermis are considered.The review continues redken shades 9gi the position of exploring the multifunctionality of the operation of all epidermal cells with their closest relationship.This multifunctionality was the main reason for the birth of such a branch of medical knowledge as morphoneuroimmunoendocrinology of the skin.